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Welcome to the Lodato Lab @ UMass Chan Medical School

The Lodato Lab studies the rates, causes, and consequences of somatic mutations in the human brain and across the body. Somatic mutations are ultra-rare and thus difficult to study using traditional methods. Therefore, we use a variety of cutting-edge single-cell genomic and bioinformatic techniques to shed light on how these mosaic variants play a role in human development, aging, and disease.


Our work on somatic mutations and cell lineage analysis in the human brain the cover of Science

Use the links below to learn more about us!

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Our Research


Meet our Team


Open Positions and Mentorship




Contact Us!

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